02. NSAIDS (NON STEROIDAL ANTI-INFLAMMATORY DRUGS) - SA Anabolics

Search
Go to content

Main menu:

02. NSAIDS (NON STEROIDAL ANTI-INFLAMMATORY DRUGS)

PRODUCT INFO > 03. ANALGESICS


NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDS) ARE A GROUP OF MEDICATIONS THAT EXERT ANALGESIC (PAIN-RELIEVING) ACTIONS IN THE BODY BY INHIBITING THE RELEASE OF INFLAMMATORY PROSTAGLANDINS.THEY DO A JOB VERY SIMILAR TO THAT OF CORTISOL, WHICH ALSO EXERTS ITS ANTI-INFLAMMATORY ACTIONS BY BLOCKING PROSTAGLANDIN BIOSYNTHESIS. A COMPARISON TO CORTISOL IS EVEN MADE IN THE TERM "NONSTEROIDAL ANTI-INFLAMMATORY" AS CORTISOL IS, OF COURSE, A STEROIDAL HORMONE WHILE THESE DRUGS ARE NOT. AS A GROUP NSAIDS ARE AMONGST THE MOST WIDELY USED PAIN MEDICINES IN THE WORLD, AND CAN BE FOUND IN A VARIETY OF PRESCRIPTION AND OVER-THE-COUNTER FORMS.THE MOST POPULAR OTC NSAIDS IN THE UNITED STATES ARE ADVIL/MOTRIN (IBUPROFEN) AND ALEVE (NAPROXEN SODIUM), WHILE CELEBREX (CELECOXIB), INDOCIN (INDOMETHACIN), VIOXX (ROFECOXIB) AND MOBIC (MELOXICAM) ARE ALL AVAILABLE BY PRESCRIPTION. ALTHOUGH ASPIRIN AND TYLENOL (ACETAMINOPHEN) ARE TECHNICALLY NOT CLASSIFIED AS NON-STEROIDAL ANTI-INFLAMMATORY DRUGS, THEY INHIBIT PROSTAGLANDIN BIOSYNTHESIS AS WELL, AND ARE THEREFORE EQUALLY RELEVANT TO OUR DISCUSSION.
ALTHOUGH NSAIDS ARE EFFECTIVE ANALGESIC MEDICATIONS, THEY ARE NOT GOOD BODYBUILDING DRUGS. THEY SHOULD NOT BE USED TO HELP YOU "WORK THROUGH THE PAIN" AND THEY WILL NOT ENHANCE YOUR RATE OF RECOVERY. IN FACT, THEY CAN BE VERY DETRIMENTAL TO MUSCLE GROWTH. THIS IS BECAUSE THE INFLAMMATORY RESPONSE THAT IS MEDIATED BY PROSTAGLANDINS IS ABSOLUTELY VITAL TO PROTEIN SYNTHESIS. IN MARCH 2002 A STUDY WAS PUBLISHED THAT MADE THIS FACT VERY CLEAR177. IT INVOLVED A GROUP OF 24 RECREATIONALLY ACTIVE YOUNG MALE SUBJECTS, WHO WERE GIVEN MAXIMUM OTC DOSES OF IBUPROFEN (1,
200MG/DAY) OR ACETAMINOPHEN (4,000MG/DAY) AND SUBJECTED TO RESISTANCE TRAINING. AMINO ACID TURNOVER WAS MEASURED FOR 24 HOURS FOLLOWING THE BOUT OF EXERCISE, WHICH ALLOWED THE INVESTIGATORS TO DETERMINE WHAT EFFECT, IF ANY, THESE DRUGS WOULD HAVE ON PROTEIN BREAKDOWN AND SYNTHESIS. IT TURNED OUT THAT BOTH IBUPROFEN AND ACETAMINOPHEN EFFECTIVELY BLUNTED THE NORMAL POST-EXERCISE RISE IN PROTEIN SYNTHESIS, WHICH WAS INCREASED 76% ABOVE BASELINE IN THE GROUP TAKING ONLY THE PLACEBO. A FOLLOW UP INVESTIGATION DEMONSTRATED THAT BOTH DRUGS WERE SPECIFICALLY BLOCKING THE NORMAL POST-EXERCISE RISE IN PGF2A178. THESE STUDIES SHOW US JUST HOW STRONGLY PROSTAGLANDINS ACTUALLY SUPPORT THE BASIC PROCESS OF MUSCLE GROWTH; THEY ARE THE LAST THINGS IN THE WORLD WE WOULD WANT TO INHIBIT WHEN TRYING TO BUILD MUSCLE.
THIS IS NOT AN OUTRIGHT CRUCIFIXION OF ANTI-INFLAMMATORY DRUGS. CERTAINLY IF YOU HAVE PAIN, THESE DRUGS ARE AMONGST YOUR SAFEST OPTIONS FOR DEALING WITH IT. I AM ALSO NOT TRYING TO SUGGEST THAT IF YOU TAKE THESE DRUGS REGULARLY YOU WILL BE TOTALLY UNABLE TO GROW. I'M SURE MANY GUYS OUT THERE WOULD
DISAGREE WITH THIS NOTION. I MYSELF HAVE TAKEN THESE DRUGS REGULARLY DURING MY TRAINING AT TIMES, AND HAVE BEEN ABLE TO MAKE PROGRESS WHILE DOING SO. BUT I CAN DEFINITELY FEEL THE DIFFERENCE WHEN THEY ARE NOT IN MY BODY; GROWTH IS MUCH LESS RESTRAINED IN COMPARISON.THE BOTTOM LINE IS THAT YOU SHOULD TAKE THESE DRUGS IF YOU NEED TO TAKE THEM. IF PAIN IS STOPPING YOU FROM BEING ABLE TO FUNCTION, YOU NEED TO TREAT THIS FIRST AND FOREMOST. BUT IF YOU DON'T NEED TO TAKE THESE DRUGS, DEFINITELY STAY THE HELL AWAY FROM THEM. NSAIDS ARE MOST CERTAINLY NOT GOING TO OFFER YOU ANY MUSCLE-BUILDING BENEFIT!
PRODUCTS AVAILIBLE IN SOUTH AFRICA

01. ABBOT SOUTH AFRICA=BRUFEN(200MG-600MG IBUPROFEN/TAB=30-100 TABS) VERY GOOD
QUALITY PRODUCT.EXCPECT TO PAY N/A
02. NORVARTIS SOUTH AFRICA=CATAFLAM(50MG DICLOFEN POTASSIUM/TAB=15 TABS)VERY GOOD
QUALITY PRODUCT.EXCPECT TO PAY N/A
03. NORVARTIS SOUTH AFRICA=VOLTAREN(25MG-100MG  DICLOFENAC SODIUM/TAB-INJECTION)VERY GOOD
QUALITY PRODUCT.EXCPECT TO PAY N/A

1.abbot sa=brufen
2.norvatis sa=cataflam
3.norvatis sa=voltaren
 
 
Back to content | Back to main menu